Single domain magnetic nanoparticles are increasingly investigated as actuators of biological and chemical processes that respond to externally applied magnetic fields. Although their localized effects have often been attributed to nanoscale heating, recent experimental evidence suggests the need to consider alternative hypotheses. Here, using the stochastic Landau–Lifshitz–Gilbert equation and finite element modeling, we investigate and critically examine an alternative hypothesis that localized effects may instead involve the induced electric fields arising from the dynamical behavior of individual single domain magnetic particles. We model the magnetization dynamics and resulting induced electric fields for two relevant and distinct cases of magnetic nanoparticles in alternating magnetic fields:(1) magnetogenetic stimulation of channel proteins associated with ferritin and (2) catalytic enhancement of …
